![]() Initiate the dosing regimen for each patient individually, taking into account the patient's underlying cause and severity of pain, prior analgesic treatment and response, and risk factors for addiction, abuse, and misuse.Reserve titration to higher doses of Morphine Sulfate Extended-Release Capsules for patients in whom lower doses are insufficiently effective and in whom the expected benefits of using a higher dose opioid clearly outweigh the substantial risks. Use the lowest effective dosage for the shortest duration of time consistent with individual patient treatment goals. ![]()
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